PAUBOX VS Microsoft 365

Microsoft 365 alone won't make your email HIPAA compliant

Microsoft's encryption relies on manual steps, locks patients in portals, and leaves gaps in inbound security. Paubox closes the gaps.

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8,000+ companies use Paubox to secure over 100 million emails every month.

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Paubox vs Microsoft 365

Feature
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Paubox Email Suite
Microsoft 365
Automatic encryption
Group 81 Paubox encrypts 100% of outbound email.
Group 91 Microsoft 365 requires users to click buttons to encrypt emails. Miss a step, email goes unencrypted.
Recipient experience
Group 81 Paubox delivers encrypted email straight to the inbox. No extra steps to read it.
Group 91 Microsoft 365 forces recipients through a 7-step portal process, often requiring a Microsoft account.
BEC and spoofing protection
Group 81 Paubox combines AI-powered inbound security with ExecProtect to verify sender identity against display names.
Group 91 Microsoft Defender checks domain reputation but can miss targeted spoofing that doesn't use malicious links.
Built for healthcare
Group 81 Paubox protects 8,000+ healthcare customers with BAA and HITRUST certification.
Group 91 Microsoft 365 is a generalist platform. Healthcare is not the priority.

Compliance gaps hiding in Microsoft 365

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No encryption, no compliance

Microsoft's encryption requires senders to manually click encrypt.

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Portals that patients can't use

It takes 7 steps to read a Microsoft-encrypted email. Recipients create accounts, manage passwords, and navigate portals.

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Security scattered across dashboards

Microsoft's settings live across Exchange Admin Center, Defender, Purview, and Entra ID. Fragmentation increases the risk of configuration gaps.

Secure every email you send and receive

encryption on autopilot

Encryption on autopilot

Paubox encrypts everything automatically and runs inside your existing Microsoft 365 email setup. No special steps for senders, no plug-ins to maintain.

no portals no passwords

No portals, no passwords

Patients and partners open messages right in their inbox. Encryption is invisible, so conversations stay moving.

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AI that adapts to your organization

Paubox layers generative AI with traditional rulesets to catch the targeted attacks that bypass Microsoft's general-purpose filters.

HIPAA compliant email security, built for healthcare

Paubox helps healthcare organizations protect PHI with built-in email encryption and AI-powered inbound threat protection. Secure patient communication without adding complexity or changing workflows.

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Automatic encryption,
without extra steps

Every message is encrypted by default, so staff never 
have to remember to click a button or add a tag. Patient data stays protected every time.

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Seamless experience for patients

Recipients can open secure emails directly in their inbox: no portals, apps, or logins required. Communication stays fast and frustration-free.

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AI-powered protection against email attacks

Stop phishing, spoofing, and malware before they reach staff. Paubox uses advanced AI to detect and block evolving email attacks.

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Start sending HIPAA compliant email today

2024-05-09_PRODCR_ProductCreative-Mar-14-2025-11-33-38-5335-PM

Outbound encryption
Automate updates to customers and internal teams on the status of test results.

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Inbound security
Automate updates to customers and internal teams on the status of test results.

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Paubox Marketing
Automate updates to customers and internal teams on the status of test results.

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healthcare organizations fell victim to email-related breaches in 2024

0%

of healthcare breaches were on Microsoft 365

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of known phishing attacks are reported by employees

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increased surge of ransomware attacks on healthcare organizations