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How data silos impact healthcare AI

Written by Gugu Ntsele | June 24, 2025

As defined in What are data silos and what problems do they cause?, "A data silo is a repository of data that's controlled by one department or business unit and isolated from the rest of an organization, much like grass and grain in a farm silo are closed off from outside elements. Siloed data typically is stored in a standalone system and often is incompatible with other data sets." 

Data silos in healthcare represent barriers to successful AI implementation. These isolated pockets of information, scattered across different departments, systems, and platforms, create a fragmented landscape that undermines the very foundation upon which effective AI models are built. 

The urgency of addressing this challenge cannot be overstated. As Sufian Chowdhury, CEO at Kinetik, explains in Healthcare Interoperability and Cloud Services – 2025 Health IT Predictions, "Healthcare spending continues to climb throughout our country, even as healthcare outcomes show little or no improvement. This massive inefficiency within the system is due to the lack of connectivity and data sharing with the healthcare ecosystem." The scale of this challenge is immense. As noted in From Data Silos to Seamless Integration: How the Cloud is Reshaping Healthcare Data Management, "the global big data market related to healthcare is expected to grow to $70 billion by 2025." This exponential growth in healthcare data volumes makes the effective management and integration of information even more important for successful AI implementation.

 

The anatomy of healthcare data silos

A typical hospital system might have dozens of different software applications, each serving a specific purpose. Electronic health records (EHRs) store patient information, laboratory information systems (LIS) manage test results, radiology information systems (RIS) handle imaging data, and pharmacy systems track medication administration. Add to this mix wearable devices, patient portals, billing systems, and research databases, and you have the ideal description of data fragmentation.

Each of these systems was often implemented at different times, by different vendors, with different standards and protocols. The result is a collection of data islands, each containing valuable information but lacking the connections necessary to create a comprehensive view of patient health. This fragmentation extends beyond technical systems to organizational boundaries, where departments guard their data, citing privacy concerns, regulatory requirements, or simply institutional inertia.

As noted in What are data silos and what problems do they cause?, "Data silos can have technical, organizational or cultural roots. They tend to arise naturally in large companies because separate business units often operate independently and have their own goals, priorities and IT budgets." This natural emergence is particularly pronounced in healthcare, where organizational structures and regulatory requirements create additional barriers to data sharing.

The problem is further compounded by the variety of data formats and standards used across healthcare. While initiatives like HL7 FHIR (Fast Healthcare Interoperability Resources) have made progress in standardizing data exchange, many systems still operate using proprietary formats or outdated standards. This makes it difficult to aggregate and harmonize data for AI applications.

 

The AI dependency on data

Artificial intelligence, particularly machine learning algorithms, are dependent on data quality and quantity. The effectiveness of AI models is directly correlated with the comprehensiveness, accuracy, and representativeness of the training data. In healthcare, where decisions can be life-or-death, this dependency becomes even more important.

As Dr. Sanjay Juneja emphasizes in his Forbes article The AI Healthcare Paradox: Why Breaking Data Silos Is Key To Generalizable, Trustworthy Models, "Even the most sophisticated AI models are only as representative as the data they ingest." This truth becomes particularly problematic when healthcare organizations operate in isolation, creating what Juneja describes as a critical flaw: "If institutions and health systems continue to train AI models solely within their own populations and geographic regions, they risk developing highly performant yet ultimately narrow-scope solutions."

Consider a predictive model designed to identify patients at risk of sepsis. To be effective, such a model needs access to a wide range of data points: vital signs from monitoring equipment, laboratory results showing infection markers, medication administration records, nursing assessments, and historical patient data. If this information is trapped in separate silos, the AI model may only see a fraction of the complete picture, leading to incomplete or inaccurate predictions.

The richness of healthcare data lies not just in individual data points but in the relationships between them. A patient's blood pressure reading becomes more meaningful when viewed alongside their medication history, recent lab results, and current symptoms. These connections and patterns are what enable AI algorithms to identify subtle correlations and generate actionable insights. Data silos break these connections, leaving AI models to work with incomplete and contextually poor datasets.

As noted by Lisa Morgan in How Data Silos Impact AI and Agents, "Fragmented datasets make it difficult for AI agents to understand context, reducing their effectiveness in decision-making and business impact." This challenge is particularly acute in healthcare, where clinical context is essential for accurate diagnosis and treatment recommendations.

 

Specific impacts on AI initiatives

Reduced model accuracy and reliability

When AI models are trained on incomplete datasets due to data silos, their accuracy and reliability suffer. As explained in What are data silos and what problems do they cause?, "Incomplete data sets. Data silos lock data away in separate data sources from users who can't access it. As a result, business strategies and decisions aren't based on all the available data, which can lead to flawed decision-making." A diagnostic AI tool that only has access to imaging data without corresponding clinical notes, lab results, or patient history will inevitably produce less accurate diagnoses than one with access to all relevant information.

The challenge is compounded by data inconsistency issues. The same article notes that "Inconsistent data. Many data silos aren't consistent with other data sources... Such inconsistencies create data quality, accuracy and integrity issues that affect end users in both operational and analytics applications." In healthcare, this might manifest as different departments formatting patient data differently, or updates made in one system not being reflected in others.

This limitation becomes problematic in healthcare, where false positives and false negatives can have serious consequences. "Data silos can pose significant risks for healthcare institutions, such as fragmented data records, inefficient data sharing, and difficulties in monitoring patient health – resulting in misdiagnoses, redundant tests, and delays in treatment," as highlighted in From Data Silos to Seamless Integration: How the Cloud is Reshaping Healthcare Data Management. A sepsis prediction model with access to only vital signs data might miss early indicators present in laboratory results, leading to delayed treatment and potentially worse outcomes. Conversely, it might generate false alarms based on isolated data points that would be clarified by additional context from other systems.

The implications extend beyond technical performance issues. As noted in the Forbes article, "In healthcare AI, localized overfitting isn't just a technical limitation—it's a matter of patient safety and trust." The article further warns that "These models may excel in their specific environments but falter when applied broadly, leading to skepticism, reduced adoption and even potential harm due to unrecognized biases."

The financial implications are substantial. According to Gordon Robinson, senior director of data management R&D at SAS, as quoted in Morgan's article, "Poor data leads to underperforming models, which can cost organizations tens of millions of dollars or more." In healthcare, these costs extend beyond financial losses to include patient safety risks and potential liability issues.

Robinson further emphasizes that "When AI models are trained on fragmented data rather than a comprehensive dataset, they fail to reach their full potential and deliver optimal insights." This underperformance can manifest in various ways, from missed diagnoses to inappropriate treatment recommendations, ultimately undermining clinician confidence in AI-powered tools.

 

Increased development time and costs

Data silos extend the timeline and increase the costs associated with AI development projects. Data scientists and engineers must spend time identifying relevant data sources, negotiating access permissions, and developing custom integration solutions. What should be a straightforward process of data extraction and preparation becomes a project involving multiple stakeholders, technical teams, and approval processes.

As Martijn Hartjes, clinical informatics business unit leader at Philips, explains in Brian Eastwood's article How Do Data Silos Impede Patient Care and Provider Efficiency?: "Siloed data retrieval demands excessive time and effort. It also makes it difficult to bring the right data to the right decision maker at the right time."

The fragmented nature of siloed data also means that resources must be devoted to data cleaning, standardization, and harmonization. Different systems may use different terminology for the same concepts, varied units of measurement, or inconsistent data formats. Addressing these inconsistencies requires specialized expertise and considerable time investment, often representing 60-80 percent of the total project effort.

Additionally, as highlighted in What are data silos and what problems do they cause?, "Duplicate data platforms and processes. Data silos add to IT costs by increasing the number of servers and data storage devices an organization must buy." This infrastructure duplication increases both initial implementation costs and ongoing maintenance expenses for AI initiatives.

The financial impact is substantial. According to IDC Market Research, as cited in What are data silos and what problems do they cause?, "incorrect or siloed data can cost a company up to 30% of its annual revenue." In healthcare, where margins are often tight and patient safety is paramount, this represents both a financial burden and a risk to care quality.

 

Limited scalability and reusability

AI models developed using data from specific silos often lack the scalability and reusability necessary for organization-wide deployment. A model trained on data from one department may not perform well when applied to similar use cases in other departments due to differences in data collection practices, patient populations, or clinical workflows.

As noted in What are data silos and what problems do they cause?, "Less collaboration between end users. Isolated data sources in silos reduce the opportunities for data sharing and collaboration between users in different departments. It's harder to work together effectively when different teams don't have visibility into siloed data." This lack of collaboration directly impacts the development and deployment of AI models that require cross-departmental input and validation.

This limitation forces organizations to develop multiple, similar models for different departments or use cases, multiplying development costs and maintenance requirements. It also creates inconsistencies in AI-driven decision-making across the organization, potentially leading to disparate care quality and patient experiences.

 

Compliance and governance challenges

Healthcare organizations operate under strict regulatory requirements, including HIPAA, FDA regulations, and various state and international privacy laws. Data silos complicate compliance efforts by making it difficult to maintain audit trails, implement consistent data governance policies, and ensure proper access controls.

The security risks are particularly concerning. As outlined in What are data silos and what problems do they cause?, "Data security and regulatory compliance issues. Some data silos are stored by individual users in Excel spreadsheets or online business tools like Google Drive, often on mobile devices. That increases data security and privacy risks for organizations if they don't have suitable controls. Silos also complicate efforts to comply with data privacy and protection laws." In healthcare, where patient data protection is paramount, these distributed and potentially unsecured data repositories create liability risks.

When data required for an AI initiative is spread across multiple silos, each with its own access controls and governance policies, ensuring compliance becomes more difficult. Organizations may need to navigate different approval processes, consent requirements, and data use agreements for each data source, slowing down AI implementation efforts.

As Robinson notes in Morgan's article, "With increasing regulatory demands and the rising frequency and cost of data breaches, robust data governance is no longer a choice -- it's a necessity." This is particularly true in healthcare, where regulatory requirements are stringent and the consequences of non-compliance can be severe.

 

Real-world consequences

The human impact of data silos extends beyond technical performance metrics. Dr. Sonja Tarrago, Director of Commercial Strategy at DexCare, captures this reality perfectly in Healthcare Interoperability and Cloud Services – 2025 Health IT Predictions: "Patients are still coming to their doctor's appointments frustrated that their provider does not have their records from a recent urgent care visit, previous primary care provider, or a specialist. And providers are still combing through years, sometimes decades, of records to understand the whole patient sitting in front of them." This fragmentation directly impacts the quality of data available for AI systems, as incomplete patient histories lead to models trained on partial information.

The growing recognition of this challenge is evident across the industry. As Shay Perera, Co-Founder and CTO at Navina, notes in the same article, "With patient data traditionally siloed, the demand for interoperable systems has never been higher. 2025 will likely be a pivotal year where we see improved but gradual integration between systems, as regulatory bodies and vendors work toward greater consistency and reliability."

 

FAQs

How do data silos affect AI’s ability to support real-time clinical decision-making?

Data silos delay the timely exchange of critical information, limiting AI’s usefulness in urgent, real-time care settings.

 

Can AI be used to help identify and break down data silos within healthcare systems?

Yes, AI can be trained to detect fragmentation and recommend patterns of data integration.

 

What role do patient-generated health data (e.g., from wearables) play in data silos?

Patient-generated data is often left out of centralized records, compounding fragmentation challenges for AI models.

 

How do siloed data environments impact the explainability or transparency of healthcare AI tools?

Incomplete datasets reduce the ability of AI models to justify decisions clearly, undermining explainability.